This Practice Note explains the regime for addressing statutory nuisance such as smoke, noise, waste, fumes, dust, insects, animals or other pollution prejudicial to health under the Environmental Protection Act 1990 (EPA 1990). It explains how EPA 1990 creates statutory nuisances offences where conduct would previously have been dealt with as public nuisances. It includes the categories of statutory nuisance under EPA 1990 which constitute an offence, including noise, waste, smoke, fumes, dust and the keeping of animals which are prejudicial to health or which cause a nuisance, elements of the offence, including the meaning of ‘prejudicial to health’ and ‘nuisance’ and penalties following conviction. It considers the power to serve an statutory nuisance abatement notice, or the power to apply to the magistrates’ court for an abatement notice. It also addresses the introduction of a statutory offence of public nuisance under the Police, Crime, Sentencing and Courts Act 2022 and the abolition of the common law offence.